A lot of SetActive

Hello friends, I have a game in which there are many monsters and I want to activate the monsters when I come to a certain area by using empty game objects as a trigger, is what I want to do the same as occlusion culling?

Occlusion culling is a graphics optimization.
What you are looking to do has to do with game mechanics, so setting those objects active / inactive is likely what you want to do. A bit more information about your situation can help clarify potential misunderstandings. But if you just want to walk into an area and have previous invisible enemies attack you, then either spawning them then and there dynamically or setting previous inactive objects active is the way to go. I’d honestly just spawn them in when i need to - and if it is ‘many monsters’ use object pooling to smooth the spawning and removing.