Advice on change sprite/animation

So I need to make a 2d game for uni, and ive not messed with the 2d component on unity much before. So Looking for some advice on a set up.

So the game is 2d, but I want the sprites to be 2.5. Going for a ‘The binding of Isaac’ style, so I want to sprite to change with what direction the sprite is facing. I have the animation set up using this site. Which all works fine, However how would I set it up to change the set of animations.

To explain it a tad better, this is the image I am using just now to test out how it works.

So the animation i have set up (using the site above) is the first four pictures from that image. But I then want it to change to the next few when ‘walking away’

I hope I have explained this well enough, if not, I can try expand if needed. Thanks

The binding of isaac is not 2.5d it is regular sprite based 2D animation.

Consider looking in the 2D learn section for proper sprite setup based on direction.
https://unity3d.com/learn/tutorials/s/2d-game-creation
https://unity3d.com/learn/tutorials/s/2d-roguelike-tutorial