Best Texture Organization for Mural-size wall art

Hello! I am currently making a VR environment that will be a set of two rooms with (hopefully) high quality continuous wall murals.
The walls are approx 20 feet long each (4 walls per room will have art on them) and I was curious about the best solution for getting the best quality textures on them. My current attempt just has them as a big honkin 4k texture with the most painting real estate I can fit on each.
Is there a better solution for this that would result in a smaller file size?
Want to make this as accessible as possible
thanks very much!

That’s kind of it.

You can use texture mip map streaming to avoid always having to have those textures loaded and letting Unity automatically load them as needed.

Or if you use the HDRP you can use Streaming Virtual Textures which kind of does the same thing but in a much more advanced way.