can we use unity physic on pure object (Graphics.DrawMeshInstanced ,etc) on GPU

can we combine unity physic with pure object from gpu?if can is there any simple example to learn?

You can install Unity.Physics without Unity.Graphics. You will still need Unity.Entities. This will allow you to have entities with physics enabled but you’ll have to figure out how to render it to the screen which you’ve already touched up on with the Graphics API.