Directions to create a "tower building game"

Hello, I’m really new to Unity, and looking to use it to produce a 2D project. I would like to start with a tower building game, like the classic SIM Tower (from Maxis).

My intention is to learn and, eventually, master the deign of this specific kind of game and then move to another.

My basic question is: can I build this kind of game with Unity? Is there some resource specific to it?

I plan to use pixel art in it, since I’m not a good designer. Thanks!

Thanks guys! I’m really new to all this, and it is nice to have your input. For now, I just want to learn about the engine. The game itself is an excuse to start a new project and get to work with Unity.

I will take a look, start trying and come back with more elaborated questions.

Thanks!