Excluding some physics collisions

I have 3 object all have a collider and rigidbody. A, B and C.

A and C can physically interact

B and C can physically interact

A and B can’t physically interact and should be able to go through each other

Is this possible to do?
thanks.

Use layers, or Physics.IgnoreCollision.

Well, you could use Layer-Based Collision Detection to make some object not collide with objects with a specific layer.

This is really easy to do via the Layer Collision Matrix which is found in Edit-> Project Settings → Phyiscs.

Create 3 layers for your A, B, C objects, then set up how they interact via the grid.