How can I get collision only on a specific object mesh?

First off, I am using Blender 2.49 and Unity 2.6.1

I would like to know if it is possible to take a Blender model (one with multiple objects or meshes like the picture shows) and get collision only on one of the objects or meshes (say the base for instance).

No matter what I try in Unity, collision seems to be an all or nothing affair when it comes to a model file. Any ideas?

Do you mean you want to detect collisions in the script for each part individually? The OnCollisionEnter function gets passed a parameter of type Collision. Although all collisions on the child objects will be reported to the root object, the collider field in the Collision object will refer to the exact collider that was hit. You can use this to access the child object and check if it is one of the ones you are interested in.

Or do you mean you want a simplified collision mesh? AFAIK in that case you need to import a separate collision object.