How to enable 'unsafe' code option when debugging using Monodevelop

When debugging from Monodevelop, Unity3D (5.3.4) overwrites the solution file and with that the Allow ‘unsafe’ code option (Assembly-CSharp->Options->Build->General->Allow ‘unsafe’ code).

How can I enable this permanently for this project?

Note that I have both gmcs.rsp and smcs.rsp in my \Assets folder (with -unsafe inside)

same problem with you, unity 5.6.2f1