How to load Scene sections with Addressables

I am very new to addressables and was wondering, in trying to reduce my CPU usage, if addressables would provide another avenue for optimization. I am working with one large scene, 4096x4096, which has many areas that could be marked/unmarked for loading. For example, I have an underground bunker, a towering office, and various passage ways. Could I use addressables to define these areas and load/unload them based on the players distance to each?