@funkyCoty I forwarded your request 
@BOXOPHOBIC the only system provided by Unity right now that allows you to target different RPs simultaneously is ShaderGraph. This is the only place where such a define would make sense.
I haven’t seen a request to add this define to ShaderGraph (also, I’m not saying there wasn’t one - I just don’t know).
We’ll definitely have a way to add RP-specific things in Block Shaders .
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