Even if it does work on ubuntu 13.04 (and on “appdb.winehq.org” it is reported to work also on ubuntu 12.10, fedora 18, linux mint 15 and arch linux), unfortunately it does not seem to work on Ubuntu 13.10 64 bit.
I have tried on Ubuntu 13.10 64 bit using the unity3d installers for versions 4.3, 4.2, 4.1 and 4.0, under both wine 1.4 (from oficial ubuntu repository) and wine 1.6 (from wine ppa “ppa:ubuntu-wine/ppa”). It installs fine (using WINEARCH=win32), starts the program fine (creating the HKLM.Software.Microsoft.WindowsNT.CurrentVersion.ProductID registry key), does not create new projects as expected, but when opening another project, even an completely empty one (an empty folder with just an empty “Assets” folder inside), the unity 3d program window opens empty. The menu bars are there, with all menu itens inside it, and the menu itens wich should open another windows indeed open them. But every window comes “empty”, just a black canvas inside the window frame.
I have tryied also some winetrick words, like corefonts, tahoma, d3dx9, forcemono, but none gave me sucess.
Also, installing Unity3D on windows xp as guest on virtualbox does not work. After installation, when trying to start the program, it complains with a popup saying “Fatal Error! Failed to initialize unity graphics”, even with virtualbox guest aditions installed, with 2D and 3D acceleration enabled, and running the virtual machine under windows or linux hosts. I have not tried yet to run on windows vista, 7 or 8 as guests.
Unity3D already have a Mac version, thus it should not be too dificult to do a linux port. Hope that, because of steam and their steam machines and SteamOS, Unity Technologies consider making a linux port of Unity3D editor, even if it would be only oficially compatible with just one distro, whichever it would be.