Is it possible to alter the files of a build when running the built application and safe that data for next execution?

Questions & Answers
1

I want to know if it’s even possible to swap for Example Prefab 1 with Prefab 2 in a built programm and to keep that change even if the programm is closed and executed again. This could be really useful for updating a programm and not having to swap the whole build each time you have to update a Prefab or something.

2

So i guess one could swap out the prefabs via JSON at runtime. How would one adress a prefab via JSON?