Is it possible to disable rendering in Unity and use something else?

Is it possible to completely disable rendering in Unity, and use some API directly via a plugin instead?
As Unity will only be used for the game logic and physics?

If you do not want any display and user input you can start the build with -batchmode
Or you just take the little Overhead and just disable all cameras / do not let the only camera render anything.

Ahh ok, and there is no problem for the plugin to “take over” the Graphics API while Unity runs on the same process?