MonoDevelop Debug vs. Release Active Configuration

I’m using Unity with MonoDevelop to edit my scripts the standard recommended way where I edit code in MonoDevelop, save the changes, then switch over to Unity where I see the little busy icon animating in the lower right corner of Unity while the changes are compiled.

I see in MonoDevelop that you can change between Debug and Release for the Active Configuration. Given the way that I’m using Unity, does it make any different which configuration I use? It doesn’t seem to…and I’m not really sure how you tell Unity to compile for a release build from within Unity itself…

Anybody have any info? Thanks.

Makes no difference since unity is doing the compiling for you.