mouse event when frame loss

The question is when the frame loss happens, would mouse events works correctly?
for example, Onmouseup and Onmousedown, if it lost the frame when mouse is released, would onmouseup be called?

No, there is no missing as i know. Cause unity horrible build-in methods like this disgusting one checks every frame - is mouse pressed, pressing or realised. Yeah, if frame in your game takes perseptible time, so

  1. your game sucks
  2. function like OnMouseDown will not give you correct information, maybe.