Hi, Im now using unity Physics.RayCastAll to test the hit things. but it always returns nothing and I cant fingerout what the problem should be.
here is the usage code.
var ray = CreateARayMethod();
hits = Physics.RaycastAll(ray, ushort.MaxValue, Physics.AllLayers);
Debug.DrawRay(ray.GetPoint(0), ray.direction * 120, Color.magenta);
the hit always returns nothing, and i sure that the ray was absolutely go through a collider.
like this.
Looks like you’re using the 3d Physics class, and not the Physics2D class for 2d physics.
Actually it was the 3D box Collider with orthographic view. 
,it look not so clearly in thee-D view.
If you’re working in 3D then that screenshot isn’t massively helpful - the ray could be starting and finishing at the wrong depth?
What’s happening in the CreateARayMethod method?
The ray was create by a snap-window mouse click event. I dont wanna put it on this page because the method is too complicated and I think I had draw it friendly on scene and take a screenshot. Actually the ray is only contruct with start point and a direction. In this case start with camera position and a dir value so it dosent matter.
The problem is , is the physic scene in unity Physics system matter? After shortly read the source code , it gose to ‘PhysicsScene.Raycast’ , can not continue without native debug experience. 
public bool Raycast(Vector3 origin, Vector3 direction, [DefaultValue("Mathf.Infinity")] float maxDistance = float.PositiveInfinity, [DefaultValue("Physics.DefaultRaycastLayers")] int layerMask = -5, [DefaultValue("QueryTriggerInteraction.UseGlobal")] QueryTriggerInteraction queryTriggerInteraction = QueryTriggerInteraction.UseGlobal)
{
float magnitude = direction.magnitude;
if (magnitude > float.Epsilon)
{
Vector3 direction2 = direction / magnitude;
return Internal_RaycastTest(ray: new Ray(origin, direction2), physicsScene: this, maxDistance: maxDistance, layerMask: layerMask, queryTriggerInteraction: queryTriggerInteraction);
}
return false;
}
I guess the colliders are not trigger colliders? Or you can,
Physics.RaycastAll(ray, Mathf.Infinity, Physics.AllLayers, Physics.queriesHitTriggers.Collide);
if they are.
After moving assets to a new blank project and rebuild all cache, it solved. What a wired bug. Thank you anyway. 
Might have been something in your project settings then.