If you set the Texture Type to “Advanced” you will see an “Extrude Edges” slider. This extends the sprite by a number of pixels as a buffer region for filtering and packing I think. That is likely the difference you’re seeing.
Isn’t it possible that the compression resizes the picture to fit into its algorithm? I noticed almost all changes are from odd to even numbers. Check if it changes when set to Truecolor. Also these are some weird texture sizes.