To me the above looks perhaps like a scaling issue, like in the second image you are deep inside some group of yellow pixels that are shown from a much further distance in the top image. This could be simply faulty scaling based on the screen dimensions, aspect ratio, or even bad anchoring if you’re using UI classes.
First step would be to isolate if this DICOM thing is failing, or if your code is somehow behaving differently.
Make a DICOM image with a known dot pattern, like a small box or an “X” or something in the middle, and see how it differs between computers with that known small test image.
Another good test image would have one pixel dead center, and display its actual and rendered coordinates onscreen on each computer, so you can reason about what is happening.
If you are using Unity UI stuff, here’s some more notes to isolate the problem:
Here are some notes on UI Anchoring, Scaling, CanvasScaler, etc: