I added a few substance materials in the scene an I’m concerned over these results.
Is it normal to have those peaks?
Did you profile the game running inside the editor?
Performance characteristics between running the game in the editor and an actual build can be quite significant. If you profiled the editor, I recommend to profile a build and check if the peaks are still there.
If you’re using Substance materials in Unity have you baked them once you’re happy with the results? Or are you changing the substance during gameplay (which will have quite an expensive cost)