It’s not about UIElements, I am using the older UI system. And I have a feeling that I encountered the same issue at some point before, but I don’t remember how I solved it. It all happened just out the blue and I can not figure out what’s causing it.
Hard to tell without seeing any code, however it looks like you somehow changed the rendering material / shader. Did you at any time call SetPass of a material somewhere in your code? Maybe you used other methods which aren’t part of the IMGUI system which may have changed the active material / pass. It looks like some sort of wireframe / outline shader.
These were called with OnGUI() method, but I moved 'em and now they are only called when a value in the list is changed. It must be noted that I do have a huge list (800+) of items, so I think that probably saving the asset each OnGUI() call was not the best idea ever lol.