I have a problem with Sprite Atlas when I use a sprite which packed in an atlas for Canvas UI.
My case: enable Tight Packing
Reproduce: I play the game, instantiate a new UI Image which uses a sprite in the atlas. It causes an issue like the image below if I disable Tight Packing and replay, the problem resolve.
If the sprites are used for UI , please disable TightPacking as I believe UI may not support tight meshes as it renders as quads. If possible please use a different atlas for UI sprites.