Unity GUI with GPU acceleration

So, I want to develop a 2D game and, of coarse, I want to use unity because I've used it for other projects and want to stick with it, especially since I'm planning on buying the pro version some day.

Anyways, my question is: Is the GUI GPU accelerated in Unity?

Why do you want to use the GUI for making a 2D game? It's far simpler to use an orthographic camera or 2D billboards or planes or similar tricks to create a 2D game.

100% of everything displayed in Unity is textures on polygons, so naturally it's all GPU accelerated. I'm not sure why you have "physics" as a tag...if you're asking about GPU-accelerated physics, no, Unity doesn't do that.