Some external libraries need to change calling conventions for Interop on x86 and x86_64. This requires a define for compilation.
Could you give an example of those different calling conventions?
Sure.
For Steamworks.NET (GitHub - rlabrecque/Steamworks.NET: Steamworks wrapper for Unity / C#) Unity 5 currently doesn’t work with the x64 version without changing to CallingConvention.ThisCall. CallingConvention.ThisCall crashes the x86 version, and requires StdCall to work. Couldn’t tell you why, Mono just falls over.
I didn’t write this library, but it has this to say on the matter:
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