Is it possible for a 2D sprite to collide with a 3D object?

So I’ve been trying to figure out if it’s possible for a 2D player sprite to be able to walk, run, jump, and shoot on a 3D model (a Cube for example) similar to DuckTales Remastered? I added an image for reference, any advice is helpful!

Just use 3D physics for everything. The 2D and 3D physics systems are separate and don’t interact, but there’s no rule saying you have to use 2D physics for sprites. Alternately, if the gameplay is purely 2D, just use 2D physics for everything…likewise there is no rule saying you have to use 3D physics for 3D objects.

–Eric

Okay I’ll try that later, Thanks!