Only Build and run works problem

Hi I have little problem in Unity. After I update my project and editor, from Unity 3.x to Unity 4.x My game working only after I use “build and run” option. After this is I try use normal exe. icon it dosent work. I see only main interface of game and nothing more. Why this is working perfect if i use buid and run, but not working in another whays? Pls help this is very important to me. Great thanks for any help.

So, if I understand correctly (correct me if not), when you use build&run from within the editor, your game runs as you expect. However, when you launch it from outside Unity through the Windows explorer, the game runs differently and not as you expect?

Stupid question just to rule out the really obvious, you’re absolutely sure you are launching from the same path you are building to?

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Yes. I fix it by adding one folder outside build folder. I had error in my Debug report:
IsolatedStorageException: Could not find a part of the path

But why Unity build works ok if i use build&run even if i dont have this folder? How it can work than? What is a different in build mode and build&run mode?